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A potential new oral drug for leishmaniasis has successfully been tested in healthy humans

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Press release July 15, 2019: Development of a new leishmaniasis drug wins EU funding

TT4CL (Targeted treatment for cutaneous leishmaniasis) is a new Horizon 2020-funded project which aims to reduce the burden of a Neglected Infectious (NID) and its social and economic impacts. Horizon 2020, the European Union’s (EU) research and innovation programme, helps...
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Dermal microdialysis: A method to determine drug levels in the skin of patients with Post kala-azar dermal leishmaniasis (PKDL). PMID: 38114040
Gert-Jan Wijnant, Srija Moulik, Kingshuk Chatterjee, Nilay K. Das, Raúl de la Flor, Katrien Van Bocxlaer, Simon L. Croft, Mitali Chatterjee. Experimental Parasitology, Volume 257, 2024,108687

Efficacy of oleylphosphocholine in experimental cutaneous leishmaniasis PMID: 37229566 Van Bocxlaer K, Dixon J, Platteeuw JJ, Van Den Heuvel D, Mcarthur KN, Harris A, Alavijeh M, Croft SL, Yardley V. J Antimicrob Chemother. 2023 Jul 5;78(7):1723-1731. doi: 10.1093/jac/dkad162.

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Leishmaniasis immunopathology-impact on design and use of vaccines, diagnostics and drugs PMID: 32152715 Kaye PM, Cruz I, Picado A, Van Bocxlaer K, Croft SL. Semin Immunopathol. 2020 Jun;42(3):247-264. doi: 10.1007/s00281-020-00788-y. Epub 2020 Mar 9.

Burza et al., Leishmaniasis, www.thelancet.com, August 17, 2018

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